Probably the majority want Anand to win. But Kramnik is awfully tough in match play. Can’t seem to be beaten as Black, and gets enough White wins to get by. Anand is going to have to come up with some new stuff in order to beat him!
Kramnik is the longtime world champion from matches; Anand won the recent WC tournament.
I would make Kramnik a substantial favorite, both because of his longevity at the very top and because it’s his sort of turf.